Proteomics - Exosomes in Senescence

Mass spectrometry analysis and visualisation

By Ryan J Wallis, PhD

This project was my introduction to bioinformatics. I utilised R/RStudio to analyse and visualise 3 large-scale mass spectrometry datasets through a combination of heatmaps, volcano plots, gene ontology, hierarchical clustering and principal component analysis (PCA). I published the majority of the work in the Journal of Extracellular Vesicles. The final dataset remains unpublished but is publicly available via the link to my thesis.

ML Techniques: Gene ontology, PCA, hierarchical clustering

SAMP_SCORE

Go to the Paper

Thesis Link

GitHub Link

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